10) Lexington, Kentucky
Known for its championship thoroughbred horse farms, bourbon distilleries and delicious eats, the “Horse Capital of the World” is a fab road trip destination for friends' or couples' getaways. Once you get there, you can leave your car parked. Town Branch Commons, the recently completed 5.5-mile greenway trail, connects the bustling downtown to the historic Bourbon Distillery District. Be one of the first guests to stay at The Manchester Hotel, a high-end boutique property that's opening in June. It's on the former grounds of Central Kentucky’s first registered bourbon distillery and boasts 125 beautiful guest rooms.
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